I'm not a huge Family Guy fan largely because I don't think its pop culture reference humor is very funny. They occasionally get a good joke out of a random reference to an obscure movie from the 1980's, but they just as often misfire. In a 22 minute episode, the references can leave me feeling bored and frustrated. "You want me to laugh at this?" I angrily ask in my mind.
But when they do story related humor or make up their own jokes, they still get a good one in there sometimes. Case in point is this scene where Peter, Bryan, Chris, and Stewie all drink ipecac and try to see who can hold out the longest. Yes, I hear you saying, it is just bodily function humor. But it's still damn funny.